The pharmacy was founded by the Jesuits in the 1713 whe Bishop István Telekessy donated a house belonging to the order for that purpose. It moved to its present site in 1900 where it functioned as a pharmacy until 1968. The museum was opened in 1987 and fitted out with restored furnishings. The furniture, made of oak with baroque rococo detailing, was purpose-built for the original Jesuit pharmacy in 1745-46.